The principles and practice of toxicogenomics: Applications and opportunities

被引:75
作者
Pennie, WD
Tugwood, JD
Oliver, GJA
Kimber, I
机构
[1] AstraZeneca, Cent Toxicol Lab, Macclesfield SK10 4TJ, Cheshire, England
[2] AstraZeneca, Pharmaceut Safety Assessment, Macclesfield SK10 4TJ, Cheshire, England
关键词
D O I
10.1093/toxsci/54.2.277
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
[No abstract available]
引用
收藏
页码:277 / 283
页数:7
相关论文
共 34 条
[1]   Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays [J].
Alon, U ;
Barkai, N ;
Notterman, DA ;
Gish, K ;
Ybarra, S ;
Mack, D ;
Levine, AJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (12) :6745-6750
[2]   Simultaneous measurement of hundreds of liver proteins: Application in assessment of liver function [J].
Anderson, NL ;
Taylor, J ;
Hofmann, JP ;
EsquerBlasco, R ;
Swift, S ;
Anderson, NG .
TOXICOLOGIC PATHOLOGY, 1996, 24 (01) :72-76
[3]   Progestin-dependent stimulation of the human leukemia inhibitory factor promoter in SKUT-1B uterine tumor cells [J].
Bamberger, AM ;
Jenatschke, S ;
Erdmann, I ;
Schulte, HM .
JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 1997, 33 (03) :189-201
[4]   Gene expression informatics - it's all in your mine [J].
Bassett, DE ;
Eisen, MB ;
Boguski, MS .
NATURE GENETICS, 1999, 21 (Suppl 1) :51-55
[5]   Options available - from start to finish - for obtaining expression data by microarray [J].
Bowtell, DDL .
NATURE GENETICS, 1999, 21 (Suppl 1) :25-32
[6]   Exploring the new world of the genome with DNA microarrays [J].
Brown, PO ;
Botstein, D .
NATURE GENETICS, 1999, 21 (Suppl 1) :33-37
[7]   AN OVERVIEW OF PRECHRONIC AND CHRONIC TOXICITY CARCINOGENICITY EXPERIMENTAL-STUDY DESIGNS AND CRITERIA USED BY THE NATIONAL TOXICOLOGY PROGRAM [J].
CHHABRA, RS ;
HUFF, JE ;
SCHWETZ, BS ;
SELKIRK, J .
ENVIRONMENTAL HEALTH PERSPECTIVES, 1990, 86 :313-321
[8]  
Dai Y, 1995, J PHARMACOL EXP THER, V275, P1614
[9]   Predictive value of in vitro model systems in toxicology [J].
Davila, JC ;
Rodriguez, RJ ;
Melchert, RB ;
Acosta, D .
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1998, 38 :63-96
[10]  
DELDAR A, 1993, DIABETES S, V42, P179