CD24 V/V is an allele associated with the risk of developing multiple sclerosis in the Spanish population

被引：37

作者：

Otaegui, D. ^{[1
]}

Saenz, A.

Camano, P.

Blazquez, L.

Goicoechea, M.

Ruiz-Martinez, J.

Olaskoaga, I.

Emparanza, J. A.

Lopez de Munain, A.

机构：

[1] Hosp Donostia, Unidad Expt, San Sebastian, Spain

[2] Hosp Mendaro, Serv Neurol, Guipuzkoa, Spain

[3] Hosp Donostia, Serv Neurol, San Sebastian, Spain

[4] Hosp Donostia, Unidad Epidemiol, San Sebastian, Spain

来源：

MULTIPLE SCLEROSIS JOURNAL | 2006年 / 12卷 / 04期

关键词：

association; Basque; CD24; multiple sclerosis; V/V;

D O I：

10.1191/135248506ms1314sr

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The allele C in the CD24 gene has been related to multiple sclerosis (MS). In this work we check this single nucleotide polymorphism (SNP) in a population of 135 patients and 285 controls. Our results confirm the association between the V/V genotype at aa 57 of this gene and MS and highlight the importance of taking into account the origin of the subjects to avoid a population bias.

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页码：511 / 514

页数：4

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