How Are Palliative Care Cancer Populations Characterized in Randomized Controlled Trials? A Literature Review

被引：19

作者：

Sigurdardottir, Katrin Ruth ^{[1
,2
,3
]}

Oldervoll, Line ^{[1
,4
]}

Hjermstad, Marianne Jensen ^{[1
,5
]}

Kaasa, Stein ^{[1
,7
]}

Knudsen, Anne Kari ^{[1
,7
]}

Lohre, Erik Torbjorn ^{[7
]}

Loge, Jon Havard ^{[1
,6
]}

Haugen, Dagny Faksvag ^{[1
,3
]}

机构：

[1] Norwegian Univ Sci & Technol NTNU, Fac Med, Dept Canc Res & Mol Med, European Palliat Care Res Ctr, N-7006 Trondheim, Norway

[2] Haraldsplass Deaconess Hosp, Sunniva Ctr Palliat Care, Bergen, Norway

[3] Haukeland Hosp, Reg Ctr Excellence Palliat Care, N-5021 Bergen, Norway

[4] Roros Rehabil Ctr, Roros, Norway

[5] Oslo Univ Hosp, Reg Ctr Excellence Palliat Care, Oslo, Norway

[6] Oslo Univ Hosp, Natl Resource Ctr Late Effects Canc Treatment, Oslo, Norway

[7] Univ Trondheim Hosp, Dept Oncol, St Olavs Hosp, N-7006 Trondheim, Norway

来源：

JOURNAL OF PAIN AND SYMPTOM MANAGEMENT | 2014年 / 47卷 / 05期

关键词：

Palliative care; literature review; randomized clinical trial; cancer; patient characteristic; generalizability; publication standard; basic data set; QUALITY-OF-LIFE; CELL LUNG-CANCER; PAINFUL BONE METASTASES; ND-YAG LASER; CONTROLLED-RELEASE MORPHINE; EXPANDABLE METAL STENTS; PHASE-III TRIAL; TRANSMUCOSAL FENTANYL CITRATE; MALIGNANT PLEURAL EFFUSIONS; SINGLE-DOSE BRACHYTHERAPY;

D O I：

10.1016/j.jpainsymman.2013.06.005

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Context. The difficulties in defining a palliative care patient accentuate the need to provide stringent descriptions of the patient population in palliative care research. Objectives. To conduct a systematic literature review with the aim of identifying which key variables have been used to describe adult palliative care cancer populations in randomized controlled trials (RCTs). Methods. The data sources used were MEDLINE (1950 to January 25, 2010) and Embase (1980 to January 25, 2010), limited to RCTs in adult cancer patients with incurable disease. Forty-three variables were systematically extracted from the eligible articles. Results. The review includes 336 articles reporting RCTs in palliative care cancer patients. Age (98%), gender (90%), cancer diagnosis (89%), performance status (45%), and survival (45%) were the most frequently reported variables. A large number of other variables were much less frequently reported. Conclusion. A substantial variation exists in how palliative care cancer populations are described in RCTs. Few variables are consistently registered and reported. There is a clear need to standardize the reporting. The results from this work will serve as the basis for an international Delphi process with the aim of reaching consensus on a minimum set of descriptors to characterize a palliative care cancer population. (C) 2014 U. S. Cancer Pain Relief Committee. Published by Elsevier Inc. All rights reserved.

引用

页码：906 / +

页数：26

共 381 条

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