Frequency of aspirin resistance in patients with congestive heart failure treated with antecedent aspirin

被引：83

作者：

Sane, DC

McKee, SA

Malinin, AI

Serebruany, VL

机构：

[1] Wake Forest Univ, Sch Med, Winston Salem, NC 27109 USA

[2] Johns Hopkins Univ, Sinai Ctr Thrombosis Res, Baltimore, MD USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2002年 / 90卷 / 08期

关键词：

D O I：

10.1016/S0002-9149(02)02718-2

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We analyzed clinical characteristics and platelet biomarkers in 88 patients with congestive heart failure treated with antecedent aspirin. The incidence of aspirin resistance was very high (57%). Until definitive clinical trials are completed, physicians should be aware of the high rate of aspirin resistance in patients with heart failure and consider clopidogrel in high-risk patients or when thromboembolism occurs despite the administration of aspirin.

引用

页码：893 / +

页数：4

共 19 条

[1] FACTORS INFLUENCING PLATELET-AGGREGATION IN WHOLE-BLOOD
ABBATE, R
FAVILLA, S
BODDI, M
COSTANZO, G
PRISCO, D
[J]. AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 1986, 86 (01) : 91 - 96
[2] Prior aspirin use predicts worse outcomes in patients with non-ST-elevation acute coronary syndromes
Alexander, JH
Harrington, RA
Tuttle, RH
Berdan, LG
Lincoff, AM
Deckers, JW
Simoons, ML
Guerci, A
Hochman, JS
Wilcox, RG
Kitt, MM
Eisenberg, PR
Califf, RM
Topol, EJ
Karsh, K
Ruzyllo, W
Stepinska, J
Widimsky, P
Boland, JB
Armstrong, PW
[J]. AMERICAN JOURNAL OF CARDIOLOGY, 1999, 83 (08) : 1147 - 1151
[3] Levels of circulating adhesion molecules in congestive heart failure and after heart transplantation
Andreassen, AK
Nordoy, I
Simonsen, S
Ueland, T
Müller, F
Froland, SS
Gullestad, L
Aukrust, P
[J]. AMERICAN JOURNAL OF CARDIOLOGY, 1998, 81 (05) : 604 - 608
[4] Role of catecholamines in platelet function: Pathophysiological and clinical significance
Anfossi, G
Trovati, M
[J]. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 1996, 26 (05) : 353 - 370
[5] FLOW CYTOMETRIC MEASUREMENT OF PLATELET-FUNCTION AND RETICULATED PLATELETS
AULT, KA
[J]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1993, 677 : 293 - 308
[6] Bhatt DL, 2001, CIRCULATION, V103, P363
[7] DING YA, 1985, J HYPERTENS, V3, pS251
[8] Antiplatelet and anticoagulant therapy in the prevention of thromboemboli in chronic heart failure
Garg, RK
Gheorghiade, M
Jafri, SM
[J]. PROGRESS IN CARDIOVASCULAR DISEASES, 1998, 41 (03) : 225 - 236
[9] Profile and prevalence of aspirin resistance in patients with cardiovascular disease
Gum, PA
Kottke-Marchant, K
Poggio, EC
Gurm, H
Welsh, PA
Brooks, L
Sapp, SK
Topol, EJ
[J]. AMERICAN JOURNAL OF CARDIOLOGY, 2001, 88 (03) : 230 - 235
[10] Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100®
Homoncik, M
Jilma, B
Hergovich, N
Stohlawetz, P
Panzer, S
Speiser, W
[J]. THROMBOSIS AND HAEMOSTASIS, 2000, 83 (02) : 316 - 321

← 1 2 →