Pregnancy Data in a Turkish Multiple Sclerosis Population

被引：21

作者：

Altintas, Ayse ^{[1
]}

Najar, Bjar ^{[2
,3
]}

Gozubatik-Celik, Gokcen ^{[1
]}

Menku, Sukriye F. ^{[1
]}

机构：

[1] Istanbul Univ, Cerrahpasa Fac Med, Dept Neurol, TR-34098 Istanbul, Turkey

[2] Malar Teaching Hosp Eskilstuna, Neurol Sect, S-63188 Eskilstuna, Sweden

[3] Malar Teaching Hosp Eskilstuna, Sect Stroke, S-63188 Eskilstuna, Sweden

来源：

EUROPEAN NEUROLOGY | 2015年 / 74卷 / 5-6期

关键词：

Multiple sclerosis; Pregnancy; Pregnancy outcome; Disease-modifying drugs; Abortion; Postpartum relapse; DISEASE-MODIFYING DRUGS; WOMEN; RISK; PROGRESSION; METAANALYSIS; DIAGNOSIS; RELAPSES; ISSUES; GENDER;

D O I：

10.1159/000441450

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: To conduct the first retrospective clinical study investigating pregnancy in Turkish multiple sclerosis (MS) patients. Summary: We evaluated 558 pregnancies in 199 MS patients and results were compared with general Turkish population's data. The fertility rate in the MS group was found to be lower than that in the general population, even before MS diagnosis was established. Our study suggests that the higher number of pregnancies may have a favorable effect on transition from relapsing-remitting MS to secondary progressive MS, although no effect has been shown regarding the possibility to reach EDSS 6.0 as a milestone. Key Messages: Our data support the conclusion that MS does not have a negative effect on the MS course and disability. (C) 2015 S. Karger AG, Basel

引用

页码：296 / 302

页数：7

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