Photo-isomerisation, triplet formation, and photo-degradation dynamics of indocyanine green solutions

被引：54

作者：

Gratz, H

Penzkofer, A ^{[1
]}

Abels, C

Szeimies, RM

Landthaler, M

Bäumler, W

机构：

[1] Univ Regensburg, Inst Expt & Angew Phys 2, D-93040 Regensburg, Germany

[2] Univ Regensburg, Dept Dermatol, D-93042 Regensburg, Germany

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY | 1999年 / 128卷 / 1-3期

关键词：

indocyanine green; dimethylsulfoxide; human plasma; intersystem crossing; tripler quantum yield; tripler lifetime; photo-isomerisation; photo-degradation; photoisomer lifetime; heating effects;

D O I：

10.1016/S1010-6030(99)00174-4

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Indocyanine green sodium iodide (ICG-NaI) in dimethylsulfoxide (DMSO), methanol, water, and human plasma is excited with a chopped powerful diode laser at 812.5 nm (time resolution 20 mu s). Small transmission changes observed are analysed in terms of triplet formation, photo-isomerisation, photo-degradation, and thermal heating. Quantum yields of P-isomer formation and T-1-triplet formation as well as P-isomer and T-1 -triplet lifetimes are determined. For nitrogen-bubbled ICG-NaI in DMSO a quantum yield of triplet formation of phi(T) approximate to 5 x 10(-5) and a triplet-state lifetime of tau(T) approximate to 700 mu s an determined. For ICG-NaI in methanol a quantum yield of P-isomer formation of phi(p) approximate to 2.4 x 10(-4) and a P-isomer lifetime of t(p) approximate to 430 mu s are obtained. (C) 1999 Elsevier Science S.A. All rights reserved.

引用

页码：101 / 109

页数：9

共 53 条

[1] Indocyanine green and laser light for the treatment of AIDS associated cutaneous Kaposi's sarcoma [J].