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The case for a US prospective cohort study of genes and environment

被引：176
作者：
Collins, FS [1 ]
机构：
[1] NHGRI, NIH, Bethesda, MD 20892 USA
来源：
NATURE | 2004年 / 429卷 / 6990期
关键词：
D O I：
10.1038/nature02628
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Information from the Human Genome Project will be vital for defining the genetic and environmental factors that contribute to health and disease. Well-designed case-control studies of people with and without a particular disease are essential for this, but rigorous and unbiased conclusions about the causes of diseases and their population-wide impact will require a representative population to be monitored over time ( a prospective cohort study). The time is right for the United States to consider such a project.
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页码：475 / 477
页数：3
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