Ricin: Mechanism of toxicity, clinical manifestations, and vaccine development. A review

被引：69

作者：

Doan, LG ^{[1
]}

机构：

[1] Colorado Sch Mines, Dept Chem, Golden, CO 80401 USA

来源：

JOURNAL OF TOXICOLOGY-CLINICAL TOXICOLOGY | 2004年 / 42卷 / 02期

关键词：

ricin; anthrax; botulinum; vaccine development;

D O I：

10.1081/CLT-120030945

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

Ricin is one of the most potent plant toxins known, and the castor plant from which it is derived, Ricinus communis, is ubiquitous. The harvesting of castor beans exceeds one million tons annually, and ricin is easier to produce than either anthrax or botulinum. As a result, ricin is a convenient, potent, and available toxin for terrorist acts. This paper will review the mechanism of toxicity, major clinical manifestations, treatment, Current methods of detection, and vaccine development.

引用

页码：201 / 208

页数：8

共 56 条

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