Specificity of IS6110-based amplification assays for Mycobacterium tuberculosis complex

被引：71

作者：

Hellyer, TJ

DesJardin, LE

Assaf, MK

Bates, JH

Cave, MD

Eisenach, KD

机构：

[1] UNIV ARKANSAS MED SCI HOSP,JOHN L MCCLELLAN MEM VET HOSP,MED RES SERV 151,LITTLE ROCK,AR 72205

[2] UNIV ARKANSAS MED SCI HOSP,DEPT PATHOL,LITTLE ROCK,AR 72205

[3] UNIV ARKANSAS MED SCI HOSP,DEPT MICROBIOL IMMUNOL,LITTLE ROCK,AR 72205

[4] UNIV ARKANSAS MED SCI HOSP,DEPT ANAT,LITTLE ROCK,AR 72205

[5] UNIV ARKANSAS MED SCI HOSP,DEPT MED,LITTLE ROCK,AR 72205

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1996年 / 34卷 / 11期

关键词：

D O I：

10.1128/JCM.34.11.2843-2846.1996

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The specificity of IS6110 for the Mycobacterium tuberculosis complex has recently been questioned. We observed no cross-reaction with 27 nontuberculous mycobacteria using strand displacement- and PCR-based amplification of the nucleotide 970 to 1026 and 762 to 865 regions of IS6110. These data support use of selected regions of IS6110 as M. tuberculosis complex-specific targets.

引用

页码：2843 / 2846

页数：4

共 27 条

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