Serial analysis of gene expression - Technical considerations and applications to cardiovascular biology

被引：33

作者：

Patino, WD ^{[1
]}

Mian, OY ^{[1
]}

Hwang, PM ^{[1
]}

机构：

[1] NHLBI, Cardiovasc Branch, NIH, Bethesda, MD 20892 USA

来源：

CIRCULATION RESEARCH | 2002年 / 91卷 / 07期

关键词：

expression; gene; cardiovascular;

D O I：

10.1161/01.RES.0000036018.76903.18

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

It has been 7 years since serial analysis of gene expression (SAGE) and microarray hybridization techniques were simultaneously introduced to allow the screening of thousands of expressed genes. Both techniques have stood up to the test of time as evidenced by their widespread use, and both have been used for studying cardiovascular diseases. SAGE has been used more extensively to study cancer cells, but it has also been used to examine gene expression in systems as divergent as rice seedlings, yeast, and Caenorhabditis elegans. In this review, a summary of the advances in SAGE technology and its unique attributes and potential applications to the cardiovascular system will be presented.

引用

收藏

页码：565 / 569

页数：5

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