Catalytic intermolecular enal-alkyne [3+2] reductive cycloadditions

被引：52

作者：

Herath, Ananda ^{[1
]}

Montgomery, John ^{[1
]}

机构：

[1] Univ Michigan, Dept Chem, Ann Arbor, MI 48109 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 43期

关键词：

D O I：

10.1021/ja0660249

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A catalytic, intermolecular [3 + 2] reductive cycloaddition of enals and alkynes has been developed. The method provides a nickel-catalyzed strategy for combining two simple acyclic π-systems into a five-membered ring product by effecting a net two-electron reduction of the starting materials mediated by triethylborane as the reducing agent. The use of a protic solvent is a key feature of the process. Copyright © 2006 American Chemical Society.

引用

页码：14030 / 14031

页数：2

共 31 条

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