Assessing the genotoxicity of industrial cutting fluids under conditions of use

被引:9
作者
Kleber, M [1 ]
Föllmann, W [1 ]
Blaszkewicz, M [1 ]
机构
[1] Univ Dortmund, Inst Arbeitsphysiol, IfADo, D-44139 Dortmund, Germany
关键词
water-soluble cutting fluids; minimist lubricant supply; decomposition products; genotoxicity;
D O I
10.1016/j.toxlet.2004.01.021
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 [卫生毒理学];
摘要
Emulsions of water-soluble cutting fluids (wsCF) and non-water-soluble cutting fluids are used in large quantities for machining processes in the metal processing industry. From toxicological and epidemiological studies health risks resulting from handling of cutting fluids are well-known. Recently, the new technology of "minimist lubricant supply" (MLS) has been introduced which uses only minimal amounts of cutting fluids, in order to reduce the costs for use and disposal. This involves higher temperatures to which the fluids are subjected. Water-soluble cutting fluids supplemented with formaldehyde donors as biocides may lead to mutagenic potential. Current data show that attention should be given to generation of other genotoxic aldehydes from cutting fluids under condition of use, referring to both conventional and "minimist lubricant supply" technologies. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:211 / 217
页数:7
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