Assessment of the efficacy, safety and quality of gentamicin use in Aberdeen Royal Infirmary

被引：6

作者：

Buabeng, KO

Mackenzie, AR

Laing, RBS ^{[1
]}

Cook, I

Jappy, B

Gould, IM

机构：

[1] Aberdeen Royal Infirm, Infect Unit, Aberdeen AB25 2ZB, Scotland

[2] Aberdeen Royal Infirm, Dept Pharm, Aberdeen AB25 2ZB, Scotland

[3] Univ Aberdeen, Dept Med Microbiol, Aberdeen AB9 1FX, Scotland

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1999年 / 44卷 / 06期

关键词：

D O I：

10.1093/jac/44.6.843

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Fifty-five patients who received od gentamicin were studied. The protocol for od gentamicin was followed in 23/55 (48%). Cure rates were 22/23 (96%) when the protocol was followed and 24/32 (75%) when not followed (P = 0.06). Toxicity was more common in those in whom the protocol was not followed (9/32; 28%) than in those in whom it was followed (1/23; 4%) (P < 0.05). The number needed to treat with the protocol to produce one additional cure was 4.84 (95% CI 2.64 to 28.66) and the number needed to treat to prevent one case of toxicity was 3.61 (95% CI 2.16 to 10.99).

引用

页码：843 / 845

页数：3

共 8 条

[1] Editorial response: Single daily dosing of aminoglycosides - A concept whose time has not yet come [J].