Objective. To evaluate the relative contributions of personal models and depression to the prediction of multiple outcomes in diabetes. Design and methods. Participants (N=111) in a randomized trial of an intervention to increase dietary self-management for diabetes patients were assessed for individual differences on three components of personal models (Seriousness, Treatment Effectiveness and Control) and depression on two occasions over a 3-month period. The predictive utility of personal models versus depression was evaluated for dietary, physiologic and quality-of-life outcomes, controlling for baseline levels. Results. Personal models and depression were relatively stable over 3 months (r=.56-.70). Personal models were predictive of outcomes in each category (eating patterns, p<.01; glycosylated haemoglobin, p<.01; physical functioning, p<.05; mental health, p<.05), whereas depression was only predictive of the mental health component of quality of life (p<.01). Conclusions. Personal models appeared to be stronger and more consistent predictors of outcome than depression. The implications of these findings were discussed in terms of the self-regulatory model and interventions to improve diabetes self-management.