Protein degradation by the proteasome and dissection of its in vivo importance with synthetic inhibitors

被引：25

作者：

Goldberg, AL

Akopian, TN

Kisselev, AF

Lee, DH

机构：

[1] Harvard Medical School,Department of Cell Biology

来源：

MOLECULAR BIOLOGY REPORTS | 1997年 / 24卷 / 1-2期

关键词：

D O I：

10.1023/A:1006860828265

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：69 / 75

页数：7

共 32 条

[1] ABNORMAL PROTEINS SERVE AS EUKARYOTIC STRESS SIGNALS AND TRIGGER THE ACTIVATION OF HEAT-SHOCK GENES [J].

ANANTHAN, J ;

GOLDBERG, AL ;

VOELLMY, R .

SCIENCE, 1986, 232 (4749) :522-524

[2]

BUSH K, 1997, IN PRESS J BIOL CHEM

[3] Structure and functions of the 20S and 26S proteasomes [J].

Coux, O ;

Tanaka, K ;

Goldberg, AL .

ANNUAL REVIEW OF BIOCHEMISTRY, 1996, 65 :801-847

[4]

CRAIU A, 1997, UNPUB

[5] DEGRADATION OF OXIDIZED INSULIN B-CHAIN BY THE MULTIPROTEINASE COMPLEX MACROPAIN (PROTEASOME) [J].

DICK, LR ;

MOOMAW, CR ;

DEMARTINO, GN ;

SLAUGHTER, CA .

BIOCHEMISTRY, 1991, 30 (10) :2725-2734

[6] Mechanistic studies on the inactivation of the proteasome by lactacystin A central role for clasto-lactacystin beta-lactone [J].

Dick, LR ;

Cruikshank, AA ;

Grenier, L ;

Melandri, FD ;

Nunes, SL ;

Stein, RL .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (13) :7273-7276

[7] INHIBITION OF PROTEASOME ACTIVITIES AND SUBUNIT-SPECIFIC AMINO-TERMINAL THREONINE MODIFICATION BY LACTACYSTIN [J].

FENTEANY, G ;

STANDAERT, RF ;

LANE, WS ;

CHOI, S ;

COREY, EJ ;

SCHREIBER, SL .

SCIENCE, 1995, 268 (5211) :726-731

[8] Functions of the proteasome in antigen presentation [J].

Goldberg, AL ;

Gaczynska, M ;

Grant, E ;

Michalek, M ;

Rock, KL .

COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1995, 60 :479-490

[9] THE MECHANISM AND FUNCTIONS OF ATP-DEPENDENT PROTEASES IN BACTERIAL AND ANIMAL-CELLS [J].

GOLDBERG, AL .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1992, 203 (1-2) :9-23

[10]

GRANT EP, 1995, J IMMUNOL, V155, P3750

← 1 2 3 4 →