Cephalezomines A-F, potent cytotoxic alkaloids from Cephalotaxus harringtonia var. nana

被引：53

作者：

Morita, H ^{[1
]}

Arisaka, M ^{[1
]}

Yoshida, N ^{[1
]}

Kobayashi, J ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Pharmaceut Sci, Sapporo, Hokkaido 0600812, Japan

来源：

TETRAHEDRON | 2000年 / 56卷 / 19期

关键词：

alkaloids; cytotoxicity; Cephalotaxus; NMR;

D O I：

10.1016/S0040-4020(00)00091-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Six new alkaloids, cephalezomines A-F (1-6), have been isolated together with known related alkaloids 7-16 from the leaves of Cephalotaxus harringtonia var. nana and the structures were elucidated by spectroscopic data and chemical methods. Cephalezomines A-F (1-6) showed potent cytotoxicity against tumor cells. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：2929 / 2934

页数：6

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