Effect of lanthanum ions on the lipid polymorphism of phosphatidylethanolamines

被引:11
作者
Hwang, F [1 ]
Zhao, DQ [1 ]
Chen, JW [1 ]
Chen, XH [1 ]
Ni, JZ [1 ]
机构
[1] ACAD SINICA,INST APPL CHEM,CHANGCHUN 130022,PEOPLES R CHINA
关键词
lanthanum; lipid polymorphism; differential scanning calorimetry; dielaidoylphosphatidylethanolamine; phosphatidylethanolamine; hexagonal II;
D O I
10.1016/0009-3084(96)02561-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The influence of lanthanum ions on the polymorphic phase of egg phosphatidylethanolamine and dielaidoylphosphatidylethanolamine (PE and DEPE) has been investigated by means of P-31-nuclear magnetic resonance (P-31-NMR) and high sensitivity differential scanning calorimetry (DSC) techniques. P-31-NMR experiments show that lanthanum ions promote the formation of the hexagonal II phase at temperatures lower than those of the pure egg PE, DSC results also show that lanthanum ions induce the formation of hexagonal II phase in DEPE liposomes even al very low ion concentration, The effect of lanthanum ions on the polymorphism of PE liposomes is much greater than that of calcium.
引用
收藏
页码:73 / 77
页数:5
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