Promotion of calcification on carboxymethylchitin discs

被引：42

作者：

Wan, ACA

Khor, E

Wong, JM

Hastings, GW

机构：

[1] NATL UNIV SINGAPORE, DEPT CHEM, SINGAPORE 119260, SINGAPORE

[2] UNIV LONDON QUEEN MARY & WESTFIELD COLL, IRC BIOMED MAT, LONDON E1 4NS, ENGLAND

[3] NATL UNIV SINGAPORE, DEPT MECH & PROD ENGN, SINGAPORE 119260, SINGAPORE

来源：

BIOMATERIALS | 1996年 / 17卷 / 15期

关键词：

carboxymethylchitin; calcification; calcium uptake; chitin;

D O I：

10.1016/0142-9612(96)89778-X

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A series of water-insoluble carboxymethylchitin (CM-chitin) discs of varying degrees of substitution (d.s.) has been investigated for their interaction with calcium phosphate. Discs of d.s. 0.03, 0.11, 0.14 and 0.23 were prepared by casting from solutions of CM-chitin in 90% formic acid. Calcium uptake and calcium phosphate nucleation were found to increase with the degree of substitution of the CM-chitin discs. The results suggest that water-insoluble CM-chitin may be useful as a platform for in vivo calcification. (C) 1996 Elsevier Science Limited.

引用

页码：1529 / 1534

页数：6

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