Connective synthesis of spirovetivanes:: Total synthesis of (±)-agarospirol, (±)-hinesol and (±)-α-vetispirene

被引：32

作者：

Maulide, N ^{[1
]}

Vanherck, JC ^{[1
]}

Markó, IE ^{[1
]}

机构：

[1] Univ Catholique Louvain, Dept Chim, B-1348 Louvain, Belgium

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2004年 / 2004卷 / 19期

关键词：

spiro compounds; total synthesis; spiroarmulation; orthoesters; diastereocontrol;

D O I：

10.1002/ejoc.2004002636

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A concise, connective synthesis of naturally occurring spirovetivanes 1 and 3, in racemic form, is presented. This novel approach involves the efficient assembly of the advanced intermediate 12 through a unique spiroannulation protocol.

引用

页码：3962 / 3967

页数：6

共 35 条

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