Novel hexahydrofuro[3,4-b]-2(1H)-pyridones from 4-aryl substituted 5-alkoxycarbonyl-6-methyl-3,6-dihydropyridones

被引：56

作者：

Morales, A ^{[1
]}

Ochoa, E ^{[1
]}

Suarez, M ^{[1
]}

Verdecia, Y ^{[1
]}

Gonzalez, L ^{[1
]}

Martin, N ^{[1
]}

Quinteiro, M ^{[1
]}

Seoane, C ^{[1
]}

Soto, JL ^{[1
]}

机构：

[1] UNIV COMPLUTENSE MADRID,FAC QUIM,DEPT QUIM ORGAN,E-28040 MADRID,SPAIN

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1996年 / 33卷 / 01期

关键词：

D O I：

10.1002/jhet.5570330118

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The tide compounds 6 have been prepared in a one-step procedure from the corresponding 4-aryl substituted 5-alkoxycarbonyl-6-methyl-3,4-dihydropyridones 4 in good yields. Quantum chemical calculations reveal a non-planar molecule with a distorted dihydropyridone ring and two favoured conformations. The C-13 nmr data and theoretical calculations support a strong push-pull effect on the olefinic moiety.

引用

页码：103 / 107

页数：5

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