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A meta-analysis of echocardiographic measurements of the left heart for the development of normative reference ranges in a large international cohort: the EchoNoRMAL study

被引：29
作者：
Doughty, R. N.
Gardin, J. M.
Hobbs, F. D. R.
McMurray, J. J. V.
Nagueh, S. F.
Poppe, K. K.
Senior, R.
Thomas, L.
Whalley, G. A.
Aune, E.
Brown, A.
Badano, L. P.
Cameron, V.
Chadha, D. S.
Chahal, N.
Chien, K. L.
Daimon, M.
Dalen, H.
Detrano, R.
Duzenli, M. Akif
Ezekowitz, J.
de Simone, G.
Di Pasquale, P.
Fukuda, S.
Gill, P. S.
Grossman, E.
Kim, H. K.
Kuznetsova, T.
Leung, N. K. W.
Linhart, A.
McDonagh, T. A.
McGrady, M.
Mill, J. G.
Mogelvang, R.
Muiesan, M. L.
Ng, A. C. T.
Ojji, D.
Otterstad, J. E.
Petrovic, D. J.
Prendergast, B.
Rietzschel, E.
Schirmer, H.
Schvartzman, P.
Simova, I.
Sliwa, K.
Stewart, S.
Squire, I. B.
Takeuchi, M.
Altman, D.
Perera, R.
机构：
[1] Univ Auckland, Auckland 1142, New Zealand
[2] Unitec Inst Technol, Auckland, New Zealand
来源：
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING | 2014年 / 15卷 / 03期
关键词：
Echocardiography; Reference ranges; Meta-analysis; LEFT-VENTRICULAR MASS; TWO-DIMENSIONAL ECHOCARDIOGRAPHY; ANGIOTENSIN-CONVERTING-ENZYME; HEALTHY JAPANESE POPULATION; LEFT ATRIAL VOLUME; SYSTOLIC DYSFUNCTION; GENERAL-POPULATION; DIASTOLIC FUNCTION; REAL-TIME; ANATOMIC VALIDATION;
D O I：
10.1093/ehjci/jet240
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
To develop age-, sex-, and ethnic-appropriate normative reference ranges for standard echocardiographic measurements of the left heart by combining echocardiographic measurements obtained from adult volunteers without clinical cardiovascular disease or significant cardiovascular risk factors, from multiple studies around the world. The Echocardiographic Normal Ranges Meta-Analysis of the Left heart (EchoNoRMAL) collaboration was established and population-based data sets of echocardiographic measurements combined to perform an individual person data meta-analysis. Data from 43 studies were received, representing 51 222 subjects, of which 22 404 adults aged 1880 years were without clinical cardiovascular or renal disease, hypertension or diabetes. Quantile regression or an appropriate parametric regression method will be used to derive reference values at the 5th and 95th centile of each measurement against age. This unique data set represents a large, multi-ethnic cohort of subjects resident in a wide range of countries. The resultant reference ranges will have wide applicability for normative data based on age, sex, and ethnicity.
引用
收藏
页码：341 / 348
页数：8
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