BMP6 orchestrates iron metabolism

被引：45

作者：

Camaschella, Clara ^{[1
,2
]}

机构：

[1] Univ Vita Salute, Milan, Italy

[2] Ist Sci San Raffaele, Div Genet & Cell Biol, Milan, Italy

来源：

NATURE GENETICS | 2009年 / 41卷 / 04期

关键词：

JUVENILE HEMOCHROMATOSIS; EXPRESSION; HEPCIDIN; HEMOJUVELIN; OVERLOAD; MOUSE;

D O I：

10.1038/ng0409-386

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The small liver peptide hepcidin is a major regulator of systemic iron homeostasis in mammals, adapting iron absorption to the body's demands. Two new studies now identify BMP6 as the key endogenous regulator of hepcidin.

引用

页码：386 / 388

页数：4

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