Synthesis of fluorescent water-soluble functionalised benzo[a]phenoxazinium salts

被引：24

作者：

Frade, Vania H. J. ^{[1
]}

Goncalves, M. Sameiro T. ^{[1
]}

Moura, Joao C. V. P. ^{[1
]}

机构：

[1] Univ Minho, Ctr Quim, P-4710057 Braga, Portugal

来源：

TETRAHEDRON LETTERS | 2006年 / 47卷 / 48期

关键词：

near-infrared dyes; functionalised probes; benzo[a]phenoxazine; fluorescent label; fluorochromophores;

D O I：

10.1016/j.tetlet.2006.09.133

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

In order to develop long-wavelength functionalised oxazine dyes with good water solubility and high photostability for biological applications, a series of novel side-chain functionalised benzo[a]phenoxazinium salts were synthesised and characterised. These polycyclic cationic compounds showed strong fluorescence in ethanol and water (pH 7.4), with an emission wavelengths higher than 637 nm, as well as high quantum yields and moderate Stokes' shifts. The photostability of the fluorophores synthesised, under irradiation at 419 nm, was good to excellent in ethanol and moderate in water at physiological pH. (c) 2006 Elsevier Ltd. All rights reserved.

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收藏

页码：8567 / 8570

页数：4

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