Glucose intolerance states in women with the polycystic ovary syndrome

被引:68
作者
Pasquali, R. [1 ]
Gambineri, A. [1 ]
机构
[1] Univ Alma Mater Studiorum, S Orsola Malpighi Hosp, Dept Med & Surg Sci DIMEC, Div Endocrinol, Bologna, Italy
关键词
Insulin resistance; insulin secretion; obesity; polycystic ovary syndrome; Type; 2; diabetes; HORMONE-BINDING GLOBULIN; TYPE-2; DIABETES-MELLITUS; PREMENOPAUSAL WOMEN; CARDIOVASCULAR-DISEASE; MEDITERRANEAN WOMEN; INSULIN-RESISTANCE; METABOLIC SYNDROME; NATURAL-HISTORY; PREVALENCE; RISK;
D O I
10.1007/BF03346757
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
The polycystic ovary syndrome (PCOS), the most common hyperandrogenic disorder affecting 4-7% of women, is often associated with metabolic alterations, chiefly insulin resistance and obesity. Based on available scientific evidence, PCOS should be regarded as an independent risk for the development of glucose intolerance states. This short review summarizes the available literature on the prevalence and incidence of impaired glucose tolerance and Type 2 diabetes in this disorder. In addition, some insights on potential factors responsible for individual susceptibility are discussed. Targeted intervention studies focused on prevention and treatment of glucose intolerance states in PCOS are warranted. (C) 2013, Editrice Kurtis
引用
收藏
页码:648 / 653
页数:6
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