Hyperjovinols A and B:: Two new phloroglucinol derivatives from Hypericum jovis with antioxidant activity in cell cultures

被引：50

作者：

Athanasas, K

Magiatis, P

Fokialakis, N

Skaltsounis, AL ^{[1
]}

Pratsinis, H

Kletsas, D

机构：

[1] Univ Athens, Dept Pharm, Lab Pharmacognosy & Nat Prod Chem, Panepistimiopolis Zografou, GR-15771 Athens, Greece

[2] NCSR Demokritos, Inst Biol, Lab Cell Proliferat & Ageing, GR-15310 Athens, Greece

来源：

JOURNAL OF NATURAL PRODUCTS | 2004年 / 67卷 / 06期

关键词：

D O I：

10.1021/np034051w

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new and four known phloroglucinol derivatives were isolated from the dichloromethane extract of the Greek endemic plant Hypericum jovis. Their antioxidant activity was evaluated in vitro with the DPPH assay and in cell cultures using the DCFH-DA assay. All six compounds demonstrated significant antioxidant activity, while two of them possessed activity at a cellular level comparable to Trolox, protecting against ROS.

引用

页码：973 / 977

页数：5

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