Manipulation of microparticles using new modes of traveling-wave-dielectrophoretic forces: Numerical simulation and experiments

被引：25

作者：

Fu, LM ^{[1
]}

Lee, GB

Lin, YH

Yang, RJ

机构：

[1] Natl Pingtung Univ Sci & Technol, Grad Inst Mat Engn, Pingtung 912, Taiwan

[2] Natl Cheng Kung Univ, Dept Engn Sci, Tainan 701, Taiwan

[3] Utech Media Inc, Tao Yuan 333, Taiwan

来源：

IEEE-ASME TRANSACTIONS ON MECHATRONICS | 2004年 / 9卷 / 02期

关键词：

numerical simulation; microparticles; traveling-wave-dielectrophoretic; yeast cells;

D O I：

10.1109/TMECH.2004.828649

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

This paper presents a microchip device which uses traveling-wave-dielectrophoretic (twDEP) forces for the manipulation of microparticles and yeast cells. The dielectrophoretic forces generated under different operating conditions are simulated numerically, and the electric field distributions, force distributions and microparticle traces are investigated thoroughly. The paper presents two innovative modes of microparticle manipulation using positive (only one electrode is active at any instant in time, while the other three electrodes are all switched off) and negative (one electrode is "off", and the other electrodes are "on") dielectrophoretic forces. Micromachining techniques are used to fabricate micro-twDEP chips. The capability of electrode arrays in manipulating bioparticles is demonstrated by driving yeast cells in a suspension medium. The current experimental data confirm that dielectrophoretic forces can be used successfully for the collection, alignment, step-wise movement and general manipulation of cells.

引用

页码：377 / 383

页数：7

共 32 条

[1] DIELECTROPHORETIC MANIPULATOR [J].

BATCHELDER, JS .

REVIEW OF SCIENTIFIC INSTRUMENTS, 1983, 54 (03) :300-302

[2]

CHAN KL, 1998, P IEEE C ENG MED BIO, P2953

[3] Micro devices integrated with microchannels and electrospray nozzles using PDMS casting techniques [J].

Chiou, CH ;

Lee, GB ;

Hsu, HT ;

Chen, PW ;

Liao, PC .

SENSORS AND ACTUATORS B-CHEMICAL, 2002, 86 (2-3) :280-286

[4] Design and fabrication of travelling wave dielectrophoresis structures [J].

Cui, L ;

Morgan, H .

JOURNAL OF MICROMECHANICS AND MICROENGINEERING, 2000, 10 (01) :72-79

[5]

Cui L, 2001, ELECTROPHORESIS, V22, P3893, DOI 10.1002/1522-2683(200110)22:18<3893::AID-ELPS3893>3.0.CO

[6]

2-2

[7]

Fuhr G., 1991, Proceedings. IEEE Micro Electro Mechanical Systems. An Investigation of Micro Structures, Sensors, Actuators, Machines and Robots (Cat. No.91CH2957-9), P259, DOI 10.1109/MEMSYS.1991.114807

[8] Dielectrophoresis of submicrometer latex spheres. 1. Experimental results [J].

Green, NG ;

Morgan, H .

JOURNAL OF PHYSICAL CHEMISTRY B, 1999, 103 (01) :41-50

[9] TRAVELING-WAVE DIELECTROPHORESIS OF MICROPARTICLES [J].

HAGEDORN, R ;

FUHR, G ;

MULLER, T ;

GIMSA, J .

ELECTROPHORESIS, 1992, 13 (1-2) :49-54

[10]

HARRISON DJ, 1998, MICRO TOTAL ANAL SYS

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