Pummerer reaction methodology for the synthesis of 5-thiophenyl substituted oxazoles

被引：24

作者：

Kreisberg, JD ^{[1
]}

Magnus, P ^{[1
]}

Shinde, S ^{[1
]}

机构：

[1] Univ Texas, Dept Chem & Biochem, Austin, TX 78712 USA

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 41期

基金：

美国国家卫生研究院;

关键词：

oxazole; diazonamide A; 5-thiophenyloxazoles;

D O I：

10.1016/S0040-4039(02)01704-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Treatment of N-acylamino-2-thiophenyl derivatives with N-chlorosuccinimide (2.0 equiv.) followed by SnCl4 (0.1-1.0 equiv.) provides a direct synthesis of 5-thiophenyloxazoles. (C) 2002 Published by Elsevier Science Ltd.

引用

页码：7393 / 7396

页数：4

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