Adherence to nebulised antibiotics in cystic fibrosis

被引：39

作者：

Latchford, Gary ^{[1
]}

Duff, Alistair ^{[3
]}

Quinn, Joanne ^{[1
]}

Conway, Steve ^{[3
]}

Conner, Mark ^{[2
]}

机构：

[1] Univ Leeds, Leeds Inst Hlth Sci, Leeds LS2 9LJ, W Yorkshire, England

[2] Univ Leeds, Inst Psychol Sci, Leeds LS2 9LJ, W Yorkshire, England

[3] St James Univ Hosp, Adult CF Unit, Leeds, W Yorkshire, England

来源：

PATIENT EDUCATION AND COUNSELING | 2009年 / 75卷 / 01期

关键词：

Cystic fibrosis; Adherence; Nebuliser; ADULTS;

D O I：

10.1016/j.pec.2008.08.027

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objective: To examine the adherence of patients with cystic fibrosis to nebulised antibiotics. Methods: A longitudinal design with adherence data collected over 12 weeks. 38 patients (mean age 24.6 years, S.D. 5.3) were recruited from an adult cystic fibrosis (CF) clinic. Adherence was electronically monitored using a Prodose adaptive aerosol delivery (AAD) device. Results: Three indices of adherence were calculated: mean percentage of times the nebuliser was used as prescribed was 50.0% (S.D. = 39.7, range 1.1, 155.6); mean percentage of days fully adhered was 31.6% (S.D. = 29.4, range 0, 97.2); mean percentage of days nebuliser used at least once was 57.1% (S.D. = 34.2, range 3.3, 100). Conclusion: Rates of adherence were generally low. Adherence was not associated with any variables apart from age. There were wide variations between individuals, and differences in rates of adherence depending on how this was defined, with potentially important health consequences for the patients. Practice implications: Technology that improves medication administration may still be associated with low rates of adherence. Health professionals need to be mindful of the pattern of non-adherence for each individual, and factors which may be influencing this. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：141 / 144

页数：4

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