Allergic symptoms and microflora in schoolchildren

被引：19

作者：

Fukuda, S ^{[1
]}

Ishikawa, H

Koga, Y

Aiba, Y

Nakashima, K

Cheng, L

Shirakawa, T

机构：

[1] Kyoto Univ, Grad Sch Publ Hlth, Dept Hlth Promot & Human Behav, Kyoto 6068501, Japan

[2] Tokai Univ, Sch Med, Dept Infect Dis, Isehara, Kanagawa 25911, Japan

来源：

JOURNAL OF ADOLESCENT HEALTH | 2004年 / 35卷 / 02期

关键词：

allergy; schoolchildren; microflora;

D O I：

10.1016/j.jadohealth.2003.09.018

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040202 ;

摘要：

We studied 867 junior high school children and administered a questionnaire documenting allergic symptoms and environmental variables, and measured Immunoglobulin E serum levels and the immunoglobulin G titers of serum antibody to microflora. A total of 716 subjects were ultimately used for statistics; those with at least two of the following allergic symptoms: asthma, rhinitis, eczema, or food allergy, showed significantly higher IgG titers to Bactroides vulgatus than other groups. This finding suggests that a species of the Bacteroides genus of the intestinal microflora. tends to affect the gut issues, but further studies are needed to clarify this. (C) Society for Adolescent Medicine, 2004.

引用

页码：156 / 158

页数：3

共 11 条

[1] Prevalence of childhood asthma, rhinitis and eczema in Scandinavia and Eastern Europe [J].

Bjorksten, B ;

Dumitrascu, D ;

Foucard, T ;

Khetsuriani, N ;

Khaitov, R ;

Leja, M ;

Lis, G ;

Pekkanen, J ;

Priftanji, A ;

Riikjarv, MA .

EUROPEAN RESPIRATORY JOURNAL, 1998, 12 (02) :432-437

[2]

Björkstén B, 1999, CLIN EXP ALLERGY, V29, P342, DOI 10.1046/j.1365-2222.1999.00560.x

[3]

Böttcher MF, 2000, CLIN EXP ALLERGY, V30, P1590, DOI 10.1046/j.1365-2222.2000.00982.x

[4] HEALTH AND THE ENVIRONMENT IN THE 1990S [J].

DOLL, R .

AMERICAN JOURNAL OF PUBLIC HEALTH, 1992, 82 (07) :933-941

[5] Aberrant composition of gut microbiota of allergic infants: a target of bifidobacterial therapy at weaning? [J].

Kirjavainen, PV ;

Arvola, T ;

Salminen, SJ ;

Isolauri, E .

GUT, 2002, 51 (01) :51-55

[6]

Martinez FD, 1999, LANCET, V354, pS12, DOI 10.1016/S0140-6736(99)90437-3

[7] High microbial turnover rate preventing atopy: a solution to inconsistencies impinging on the Hygiene hypothesis? [J].

Matricardi, PM ;

Bonini, S .

CLINICAL AND EXPERIMENTAL ALLERGY, 2000, 30 (11) :1506-1510

[8] Bacteroides ovatus as the predominant commensal intestinal microbe causing a systemic antibody response in inflammatory bowel disease [J].

Saitoh, S ;

Noda, S ;

Aiba, Y ;

Takagi, A ;

Sakamoto, M ;

Benno, Y ;

Koga, Y .

CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, 2002, 9 (01) :54-59

[9] Intestinal microflora of Estonian and Swedish infants [J].

Sepp, E ;

Julge, K ;

Vasar, M ;

Naaber, P ;

Bjorksten, B ;

Mikelsaar, M .

ACTA PAEDIATRICA, 1997, 86 (09) :956-961

[10] The inverse association between tuberculin responses and atopic disorder [J].

Shirakawa, T ;

Enomoto, T ;

Shimazu, S ;

Hopkin, JM .

SCIENCE, 1997, 275 (5296) :77-79

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