Phox2 genes -: from patterning to connectivity

被引：185

作者：

Brunet, JF ^{[1
]}

Pattyn, A ^{[1
]}

机构：

[1] Ecole Normale Super, CNRS UMR 8542, F-75005 Paris, France

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2002年 / 12卷 / 04期

关键词：

D O I：

10.1016/S0959-437X(02)00322-2

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In the developing brain, many transcription factors are expressed in complex patterns and dynamics, and drive the differentiation of many classes of neurons. How does the spatio-temporal landscape of transcription factor expression map onto the bewildering variety of neuronal types, and, for each of them, the variety of developmental stages they go through? In other words, what is the logic in the transcriptional control of neuronal differentiation? Here, we review what recent work on the two neuronal-type-specific transcription factors Phox2a and Phox2b has contributed to our understanding of this broad question.

引用

页码：435 / 440

页数：6

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