Early infection and subsequent insulin dependent diabetes

被引：56

作者：

Gibbon, C

Smith, T

Egger, P

Betts, P

Phillips, D

机构：

[1] UNIV SOUTHAMPTON,METAB PROGRAMMING GRP,MRC,ENVIRONM EPIDEMIOL UNIT,SOUTHAMPTON,HANTS,ENGLAND

[2] SOUTHAMPTON GEN HOSP,DEPT CHILD HLTH,SOUTHAMPTON,HANTS,ENGLAND

来源：

ARCHIVES OF DISEASE IN CHILDHOOD | 1997年 / 77卷 / 05期

关键词：

insulin dependent (type 1) diabetes; infancy; infection; case-control study;

D O I：

10.1136/adc.77.5.384

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

In a study of 58 children under the age of 16 with insulin dependent diabetes (IDDM) and 172 matched non-diabetic controls, infection during the first year of life was associated with a reduction in diabetes risk (odds ratio 0.81, 95% confidence interval 0.67 to 0.98, per infective episode). Decreased exposure to common infections during infancy may be linked with subsequent IDDM.

引用

页码：384 / 385

页数：2

共 6 条

[1] BLOM L, 1989, DIABETOLOGIA, V32, P7
[2] INCREASING INCIDENCE OF IDDM A CONSEQUENCE OF IMPROVED HYGIENE
KOLB, H
ELLIOTT, RB
[J]. DIABETOLOGIA, 1994, 37 (07) : 729 - 729
[3] THE GENETICS AND EPIDEMIOLOGY OF DIABETES IN NOD MICE
LEITER, EH
SERREZE, DV
PROCHAZKA, M
[J]. IMMUNOLOGY TODAY, 1990, 11 (05): : 147 - 149
[4] Epidemiology of childhood IDDM in Northern Ireland 1989-1994: Low incidence in areas with highest population density and most household crowding
Patterson, CC
Carson, DJ
Hadden, DR
[J]. DIABETOLOGIA, 1996, 39 (09) : 1063 - 1069
[5] SCHWIMMBECK PL, 1988, J IMMUNOL, V140, P3394
[6] PERSISTENT MHV (MOUSE HEPATITIS-VIRUS) INFECTION REDUCES THE INCIDENCE OF DIABETES-MELLITUS IN NONOBESE DIABETIC MICE
WILBERZ, S
PARTKE, HJ
DAGNAESHANSEN, F
HERBERG, L
[J]. DIABETOLOGIA, 1991, 34 (01) : 2 - 5

← 1 →