The interaction of vitamin K1 with phospholipid membranes

被引：5

作者：

Asai, Y ^{[1
]}

机构：

[1] Eisai & Co Ltd, Formulat Res Lab, Kawashima, Gifu 5016195, Japan

来源：

COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS | 2000年 / 163卷 / 2-3期

关键词：

surface monolayer; solid phase; bulk phase;

D O I：

10.1016/S0927-7757(99)00317-9

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 [物理化学]; 081704 [应用化学];

摘要：

The effects of vitamin K-1 (VK) on dipalmitoylphosphatidylcholine (DPPC) membrane were studied by surface monolayer, differential scanning calorimetry and fluorescence techniques. DPPC and VK are proved to be freely miscible in the mixed monolayer at an air/water interface, and to be partially miscible in bulk phase, i.e. bilayer and solid phase. There is a condensing interaction between VK and DPPC in the VK/DPPC mixed monolayers. The solubility of VK in the DPPC is about 20 mol% and the solubility of DPPC in VK is about 10 mol%. The membrane fluidity of DPPC was increased by the addition of VK and the phase transition temperature was decreased. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：265 / 270

页数：6

共 13 条

[1]

Dunphy P.J., 1971, METHODS ENZYMOLOGY, VVolume 18, P407, DOI [10.1016/S0076-6879(71)18035-4, DOI 10.1016/S0076-6879(71)18035-4]

[2]

Fieser LF, 1941, J BIOL CHEM, V137, P659

[3]

LATERAL DIFFUSION IN HYDROPHOBIC REGION OF MEMBRANES - USE OF PYRENE EXCIMERS AS OPTICAL PROBES [J].

GALLA, HJ ;

SACKMANN, E .

BIOCHIMICA ET BIOPHYSICA ACTA, 1974, 339 (01) :103-115

[4]

PHOSPHOLIPID MONOLAYERS AT THE TRIOLEIN SALINE INTERFACE - PRODUCTION OF MICROEMULSION PARTICLES AND CONVERSION OF MONOLAYERS TO BILAYERS [J].

HANDA, T ;

SAITO, H ;

MIYAJIMA, K .

BIOCHEMISTRY, 1990, 29 (11) :2884-2890

[5]

HANDA T, 1985, PROG COLL POL SCI S, V71, P26

[6]

FORMATION AND STRUCTURE OF STABLY DISPERSED SMALL PARTICLES COMPOSED OF PHOSPHATIDYLCHOLINE AND UBIQUINONE-10 - COEXISTENCE OF EMULSION PARTICLES WITH BILAYER VESICLES [J].

HANDA, T ;

ASAI, Y ;

MIYAJIMA, K ;

KAWASHIMA, Y ;

KAYANO, M ;

IDA, K ;

IKEUCHI, T .

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1991, 143 (01) :205-213

[7]

INTERACTIONS AND STRUCTURE-ORGANIZATIONS OF MENAQUINONE-4 AND EGG-YOLK PHOSPHATIDYLCHOLINE MIXTURES - FORMATION OF BILAYER AND NONBILAYER STRUCTURES IN AN AQUEOUS-MEDIUM [J].

HANDA, T ;

ASAI, Y ;

KOMATSU, H ;

MIYAJIMA, K .

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1992, 153 (02) :303-313

[8]

JOHNSON BC, 1981, MOL CELL BIOCHEM, V38, P77

[9]

INTERACTION OF DIFFERENTLY ORIENTED LIPIDS IN MONOLAYER - MIXED MONOLAYERS OF 16-(9-ANTHROYLOXY)PALMITIC ACID WITH PHOSPHATIDYLCHOLINE AND CHOLESTEROL [J].

NAKAGAKI, M ;

TOMITA, K ;

HANDA, T .

BIOCHEMISTRY, 1985, 24 (17) :4619-4624

[10]

VITAMIN-K-DEPENDENT CARBOXYLASE [J].

SUTTIE, JW .

ANNUAL REVIEW OF BIOCHEMISTRY, 1985, 54 :459-477

← 1 2 →