A simple and efficient enantioselective synthesis of 2-alkylidene-3-alkyl-1,4-benzodioxanes by palladium-catalyzed annulation of benzene-1,2-diol and propargylic carbonates

被引：69

作者：

Labrosse, JR ^{[1
]}

Lhoste, P ^{[1
]}

Sinou, D ^{[1
]}

机构：

[1] Univ Lyon 1, CNRS, Lab Synth Asymetr, CPE Lyon, F-69622 Villeurbanne, France

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 04期

关键词：

D O I：

10.1021/ol9913791

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Benzene-1,2 diol reacts with various propargylic carbonates in the presence of a palladium catalyst and a chiral atropoisomeric diphosphine to give 2 alkylidene 3-alkyl-1,4-benzodioxanes in good yields and 56-97% enantiomeric excess.

引用

页码：527 / 529

页数：3

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