Advances in structure analysis using small-angle scattering in solution

被引:145
作者
Svergun, DI
Koch, MHJ
机构
[1] EMBL, Hamburg Outstn, D-22603 Hamburg, Germany
[2] Russian Acad Sci, Inst Crystallog, Moscow 117333, Russia
关键词
D O I
10.1016/S0959-440X(02)00363-9
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The resolution and reliability of solution scattering models have been significantly improved by ab initio shape and domain structure determination, and by detailed modelling of macromolecular complexes using rigid-body refinement. Substantial progress has also been made in the quantitative analysis and modelling of assembly and folding processes, and intermolecular interactions.
引用
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页码:654 / 660
页数:7
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