Chemical-inducible systems for regulated expression of plant genes

被引:148
作者
Zuo, JR [1 ]
Chua, NH [1 ]
机构
[1] Rockefeller Univ, Plant Mol Biol Lab, New York, NY 10021 USA
关键词
D O I
10.1016/S0958-1669(00)00073-2
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Chemical regulation of transgene expression presents a powerful tool for basic research in plant biology and biotechnological applications. Various chemical-inducible systems based on de-repression, activation and inactivation of the target gene have been described. The utility of inducible promoters has been successfully demonstrated by the development of a marker-free transformation system and large-scale gene profiling. In addition, field applications appear to be promising through the use of registered agrochemicals (e.g. RH5992) as inducers.
引用
收藏
页码:146 / 151
页数:6
相关论文
共 28 条
[1]   A glucocorticoid-mediated transcriptional induction system in transgenic plants [J].
Aoyama, T ;
Chua, NH .
PLANT JOURNAL, 1997, 11 (03) :605-612
[2]  
Aoyama T, 1999, INDUCIBLE GENE EXPRESSION IN PLANTS, P43
[3]   Generation of conditional mutants in higher eukaryotes by switching between the expression of two genes [J].
Baron, U ;
Schnappinger, D ;
Helbl, V ;
Gossen, M ;
Hillen, W ;
Bujard, H .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (03) :1013-1018
[4]  
Berger F, 1998, CELL MOL BIOL, V44, P711
[5]   Transcriptional activator TGV mediates dexamethasone-inducible and tetracycline-inactivatable gene expression [J].
Böhner, S ;
Lenk, I ;
Rieping, M ;
Herold, M ;
Gatz, C .
PLANT JOURNAL, 1999, 19 (01) :87-95
[6]   Expression profiling of the maize flavonoid pathway genes controlled by estradiol-inducible transcription factors CRC and P [J].
Bruce, W ;
Folkerts, O ;
Garnaat, C ;
Crasta, O ;
Roth, B ;
Bowen, B .
PLANT CELL, 2000, 12 (01) :65-79
[7]   An ethanol inducible gene switch for plants used to manipulate carbon metabolism [J].
Caddick, MX ;
Greenland, AJ ;
Jepson, I ;
Krause, KP ;
Qu, N ;
Riddell, KV ;
Salter, MG ;
Schuch, W ;
Sonnewald, U ;
Tomsett, AB .
NATURE BIOTECHNOLOGY, 1998, 16 (02) :177-180
[8]   Root development: Quiescent center not so mute after all [J].
Doerner, P .
CURRENT BIOLOGY, 1998, 8 (02) :R42-R44
[9]   TN10-ENCODED TET-REPRESSOR CAN REGULATE AN OPERATOR-CONTAINING PLANT PROMOTER [J].
GATZ, C ;
QUAIL, PH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (05) :1394-1397
[10]   Promoters that respond to chemical inducers [J].
Gatz, C ;
Lenk, I .
TRENDS IN PLANT SCIENCE, 1998, 3 (09) :352-358