Commentary: SPG7 is an essential and conserved component of the mitochondrial permeability transition pore

被引:23
作者
Bernardi, Paolo [1 ]
Forte, Michael [2 ]
机构
[1] Univ Padua, Dept Biomed Sci, Padua, Italy
[2] Oregon Hlth & Sci Univ, Vollum Inst, Portland, OR 97201 USA
关键词
mitochondria; permeability transition pore; SPG7; paraplegin; cell death; HEREDITARY SPASTIC PARAPLEGIA; PERIPHERAL BENZODIAZEPINE-RECEPTOR; F-ATP SYNTHASE; M-AAA PROTEASE; CYCLOPHILIN-D; CELL-DEATH; CHANNEL FORMATION; MEMBRANE; LIGANDS;
D O I
10.3389/fphys.2015.00320
中图分类号
Q4 [生理学];
学科分类号
071003 [生理学];
摘要
引用
收藏
页数:3
相关论文
共 24 条
[1]
An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore [J].
Alavian, Kambiz N. ;
Beutner, Gisela ;
Lazrove, Emma ;
Sacchetti, Silvio ;
Park, Han-A ;
Licznerski, Pawel ;
Li, Hongmei ;
Nabili, Panah ;
Hockensmith, Kathryn ;
Graham, Morven ;
Porter, George A., Jr. ;
Jonas, Elizabeth A. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (29) :10580-10585
[2]
Loss of m-AAA protease in mitochondria causes complex I deficiency and increased sensitivity to oxidative stress in hereditary spastic paraplegia [J].
Atorino, L ;
Silvestri, L ;
Koppen, M ;
Cassina, L ;
Ballabio, A ;
Marconi, R ;
Langer, T ;
Casari, G .
JOURNAL OF CELL BIOLOGY, 2003, 163 (04) :777-787
[3]
Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death [J].
Baines, Christopher P. ;
Kaiser, Robert A. ;
Sheiko, Tatiana ;
Craigen, William J. ;
Molkentin, Jeffery D. .
NATURE CELL BIOLOGY, 2007, 9 (05) :550-U122
[4]
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death [J].
Baines, CP ;
Kaiser, RA ;
Purcell, NH ;
Blair, NS ;
Osinska, H ;
Hambleton, MA ;
Brunskill, EW ;
Sayen, MR ;
Gottlieb, RA ;
Dorn, GW ;
Robbins, J ;
Molkentin, JD .
NATURE, 2005, 434 (7033) :658-662
[5]
Properties of the permeability transition pore in mitochondria devoid of cyclophilin D [J].
Basso, E ;
Fante, L ;
Fowlkes, J ;
Petronilli, V ;
Forte, MA ;
Bernardi, P .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (19) :18558-18561
[6]
THE MITOCHONDRIAL PERMEABILITY TRANSITION PORE: CHANNEL FORMATION BY F-ATP SYNTHASE, INTEGRATION IN SIGNAL TRANSDUCTION, AND ROLE IN PATHOPHYSIOLOGY [J].
Bernardi, Paolo ;
Rasola, Andrea ;
Forte, Michael ;
Lippe, Giovanna .
PHYSIOLOGICAL REVIEWS, 2015, 95 (04) :1111-1155
[7]
The mitochondrial permeability transition pore: a mystery solved? [J].
Bernardi, Paolo .
FRONTIERS IN PHYSIOLOGY, 2013, 4
[8]
Channel Formation by Yeast F-ATP Synthase and the Role of Dimerization in the Mitochondrial Permeability Transition [J].
Carraro, Michela ;
Giorgio, Valentina ;
Sileikyte, Justina ;
Sartori, Geppo ;
Forte, Michael ;
Lippe, Giovanna ;
Zoratti, Mario ;
Szabo, Ildiko ;
Bernardi, Paolo .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2014, 289 (23) :15980-15985
[9]
Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease [J].
Casari, G ;
De Fusco, M ;
Ciarmatori, S ;
Zeviani, M ;
Mora, M ;
Fernandez, P ;
De Michele, G ;
Filla, A ;
Cocozza, S ;
Marconi, R ;
Dürr, A ;
Fontaine, B ;
Ballabio, A .
CELL, 1998, 93 (06) :973-983
[10]
Inhibition of the mitochondrial F1F0-ATPase by ligands of the peripheral benzodiazepine receptor [J].
Cleary, Joanne ;
Johnson, Kathryn M. ;
Opipari, Anthony W. ;
Glick, Gary D. .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2007, 17 (06) :1667-1670