Neural Mechanisms of Cardioprotection

被引：56

作者：

Gourine, Andrey ^{[1
]}

Gourine, Alexander V. ^{[2
]}

机构：

[1] Karolinska Univ Hosp, Karolinska Inst, Dept Cardiol, Stockholm, Sweden

[2] UCL, London, England

来源：

PHYSIOLOGY | 2014年 / 29卷 / 02期

基金：

英国惠康基金;

关键词：

ACUTE MYOCARDIAL-INFARCTION; ISCHEMIA-REPERFUSION INJURY; CHANNEL-DEPENDENT MECHANISM; AUTONOMIC NERVOUS-SYSTEM; SPINAL-CORD STIMULATION; K-ATP CHANNELS; VAGAL-STIMULATION; CORONARY-OCCLUSION; RAT-HEART; PRECONDITIONING PROTECTS;

D O I：

10.1152/physiol.00037.2013

中图分类号：

Q4 [生理学];

学科分类号：

071003 [生理学];

摘要：

This review highlights the importance of neural mechanisms capable of protecting the heart against lethal ischemia/reperfusion injury. Increased parasympathetic (vagal) activity limits myocardial infarction, and recent data suggest that activation of autonomic reflex pathways contributes to powerful innate mechanisms of cardioprotection underlying the remote ischemic conditioning phenomena.

引用

页码：133 / 140

页数：8

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