Comparative usefulness of inflammatory markers to indicate bacterial infection-analyzed according to blood culture results and related clinical factors

被引：8

作者：

Nishikawa, Hirokazu ^{[1
]}

Shirano, Michinori ^{[2
]}

Kasamatsu, Yu ^{[2
]}

Morimura, Ayumi ^{[2
]}

Iida, Ko ^{[2
]}

Kishi, Tomomi ^{[2
]}

Goto, Tetsushi ^{[2
]}

Okamoto, Saki ^{[1
]}

Ehara, Eiji ^{[1
,3
]}

机构：

[1] Osaka City Gen Hosp, Dept Clin Lab, Miyakojima Ku, Osaka, Osaka 5340021, Japan

[2] Osaka City Gen Hosp, Dept Infect Dis, Miyakojima Ku, Osaka, Osaka 5340021, Japan

[3] Osaka City Gen Hosp, Dept Pediat Cardiol, Miyakojima Ku, Osaka, Osaka 5340021, Japan

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2016年 / 84卷 / 01期

关键词：

Bacterial infection; C-reactive protein; Procalcitonin; Systemic inflammatory response syndrome; Organ failure; C-REACTIVE PROTEIN; SERUM PROCALCITONIN; SEPSIS; METAANALYSIS; DEFINITIONS; PNEUMONIA;

D O I：

10.1016/j.diagmicrobio.2015.09.015

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

To assess relationships of inflammatory markers and 2 related clinical factors with blood culture results, we retrospectively investigated inpatients' blood culture and blood chemistry findings that were recorded from January to December 2014 using electronic medical records and analyzed the data of 852 subjects (426 culture-positive and 426 culture-negative). Results suggested that the risk of positive blood culture statistically increased as inflammatory marker levels and the number of related factors increased. Concerning the effectiveness of inflammatory markers, when the outcome definition was also changed for C-reactive protein (CRP), the odds ratio had a similar value, whereas when the outcome definition of blood culture positivity was used for procalcitonin (PCT), the greatest effectiveness of that was detected. Therefore, the current results suggest that PCT is more useful than CRP as an auxiliary indication of bacterial infection. (C) 2016 Elsevier Inc. All rights reserved.

引用

页码：69 / 73

页数：5

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