Inositol versus placebo augmentation of serotonin reuptake inhibitors in the treatment of obsessive-compulsive disorder: a double-blind cross-over study

被引：55

作者：

Fux, M

Benjamin, J

Belmaker, RH

机构：

[1] Ben Gurion Univ Negev, Fac Hlth Sci, Minist Hlth, Mental Hlth Ctr, Beer Sheva, Israel

[2] Ben Gurion Univ Negev, Fac Hlth Sci, Dept Psychiat, Soroka Med Ctr,Kupat Holim Sick Fund, Beer Sheva, Israel

来源：

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY | 1999年 / 2卷 / 03期

关键词：

augmentation; inositol; obsessive-compulsive disorder; serotonin reuptake inhibitors;

D O I：

10.1017/S1461145799001546

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Current serotonin reuptake inhibitor (SRI) treatments for obsessive-compulsive disorder (OCD) provide only partial benefit. A previous study suggested that inositol alone is efficacious in OCD. Ten DSM-IV OCD patients completed a study of 18 g inositol or placebo for 6 wk each in addition to ongoing SRI treatment in a double-blind randomized cross-over design. Weekly assessments included the Yale-Brown Obsessive-Compulsive Scale (YBOCS) and Hamilton Depression and Anxiety scales. No significant difference was found between the two treatment phases.

引用

页码：193 / 195

页数：3

共 12 条

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