Current Concepts: Rhabdomyolysis and Acute Kidney Injury.

被引：897

作者：

Bosch, Xavier ^{[1
]}

Poch, Esteban ^{[2
]}

Grau, Josep M. ^{[1
]}

机构：

[1] Univ Barcelona, Muscle Res Unit, Dept Internal Med, Hosp Clin,Inst Invest Biomed August Pi & Sunyer, E-08036 Barcelona, Spain

[2] Univ Barcelona, Dept Nephrol, Hosp Clin, Inst Invest Biomed August Pi & Sunyer, E-08036 Barcelona, Spain

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2009年 / 361卷 / 01期

关键词：

ACUTE-RENAL-FAILURE; TRAUMATIC RHABDOMYOLYSIS; FLUID RESUSCITATION; LIPID-PEROXIDATION; CREATINE-KINASE; MYOGLOBIN; MANNITOL; MECHANISMS; SERUM; PATHOPHYSIOLOGY;

D O I：

10.1056/NEJMra0801327

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The causes of acute rhabdomyolysis include trauma, drugs, toxins, and certain infections. Acute kidney injury is a dangerous complication of severe rhabdomyolysis. This review summarizes current views on the pathogenesis of myoglobin-induced kidney injury as well as on its prevention and treatment. Copyright © 2009 Massachusetts Medical Society.

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页码：62 / 72

页数：11

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