Stable thioaldehydes: Synthesis, structure assignment, and stability of 6-amino-5-thioformyluracils

被引：5

作者：

Hirota, K ^{[1
]}

Sajiki, H ^{[1
]}

Kubo, K ^{[1
]}

Kido, M ^{[1
]}

Nakagawa, K ^{[1
]}

机构：

[1] OTSUKA PHARMACEUT CO LTD,TOKUSHIMA RES INST,TOKUSHIMA 77101,JAPAN

来源：

TETRAHEDRON | 1996年 / 52卷 / 30期

关键词：

D O I：

10.1016/0040-4020(96)00533-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Stable 6-amino-5-thioformyluracils fair were synthesized starting from 6-amino-1,3-disubstituted uracils 1a-e in 23-98 % yields. According to the x-ray crystal structure, although the thioaldehyde 3c possesses reasonable double-bond character of the C=S bond the length of C=S bond of the thioaldehyde 3c is longer than those of the kinetically stabilized thioaldehydes due to the mesomeric effect of the 6-amino group. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：9971 / 9978

页数：8

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