Understanding the Words of Chromatin Regulation

被引：295

作者：

Wu, Jiang I. ^{[1
,2
]}

Lessard, Julie ^{[1
,2
]}

Crabtree, Gerald R. ^{[1
,2
]}

机构：

[1] Stanford Univ, Howard Hughes Med Inst, Dept Pathol, Stanford, CA 94062 USA

[2] Stanford Univ, Howard Hughes Med Inst, Dept Dev Biol, Stanford, CA 94062 USA

来源：

CELL | 2009年 / 136卷 / 02期

关键词：

REMODELING COMPLEX; POLYCOMB GROUP; HISTONE H3; BRG1; ISWI; EXPRESSION; SUBUNIT; DISRUPTION; PROTEINS; GENES;

D O I：

10.1016/j.cell.2009.01.009

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent studies indicate that chromatin regulatory complexes produce biological specificity in the way that letters produce meanings by combinations into words. Combinatorial assembly of chromatin regulatory complexes may be critical for maximizing the information content provided by arrays of histone modifications.

引用

收藏

页码：200 / 206

页数：7

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