The study of the photokilling effect and mechanism of ultrafine TiO2 particles on U937 cells

被引：69

作者：

Huang, NP ^{[1
]}

Xu, MH ^{[1
]}

Yuan, CW ^{[1
]}

Yu, RR ^{[1
]}

机构：

[1] NANJING UNIV,DEPT BIOCHEM,NANJING 210093,PEOPLES R CHINA

来源：

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY | 1997年 / 108卷 / 2-3期

关键词：

ultrafine TiO2 particles; photocatalytic killing effect; U937; cells; reactive oxygen species;

D O I：

10.1016/S1010-6030(97)00093-2

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The killing effect of photoexcited ultrafine TiO2 particles (UFP TiO2) on U937 cells has been studied. The mechanism concerned has been further investigated by DNA agarose gel electrophoresis. The electrophorogram shows that reactive oxygen species produced by photoexcited UFP TiO2 can damage DNA, which results in cell death. Finally, a new assumption of the way to kill cancer cells is proposed. (C) 1997 Elsevier Science S.A.

引用

页码：229 / 233

页数：5

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