Expression of four housekeeping proteins in elderly patients with schizophrenia

被引：49

作者：

Bauer, Deborah Elaine ^{[1
,2
]}

Haroutunian, Vahram ^{[3
]}

McCullumsmith, Robert E. ^{[1
]}

Meador-Woodruff, James H. ^{[1
]}

机构：

[1] Univ Alabama Birmingham, Dept Psychiat & Behav Neurobiol, Birmingham, AL 35294 USA

[2] Univ Michigan, Neurosci Program, Ann Arbor, MI 48109 USA

[3] Mt Sinai Sch Med, Dept Psychiat, New York, NY USA

来源：

JOURNAL OF NEURAL TRANSMISSION | 2009年 / 116卷 / 04期

关键词：

VCP; GAPDH; Anterior cingulate cortex; Dorsolateral prefrontal cortex; Hippocampus; Primary visual cortex; WESTERN-BLOT;

D O I：

10.1007/s00702-008-0143-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We compared protein expression by Western blot analysis in four areas of postmortem brain from patients with schizophrenia and control subjects for several proteins that are often used as controls for Western blot studies: beta-tubulin, actin, glyceraldehyde-3-phosphate dehydrogenase, and valosin-containing protein. We did not detect any differences in expression between subjects with schizophrenia and a comparison group. These results suggest that all four proteins are suitable loading controls for postmortem studies of schizophrenia.

引用

页码：487 / 491

页数：5

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