The Stomach in Diabetes: From Villain to Ally

被引：22

作者：

Camilleri, Michael ^{[1
]}

机构：

[1] Mayo Clin, Miles & Shirley Fiterman Ctr Digest Dis, Coll Med, CENTER, Rochester, MN 55905 USA

来源：

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY | 2009年 / 7卷 / 03期

关键词：

GASTROINTESTINAL-TRACT; MELLITUS; GASTROPARESIS; SYMPTOMS; SURGERY; LIFE;

D O I：

10.1016/j.cgh.2008.10.031

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

The stomach is commonly the source of chronic digestive symptoms in patients with diabetes mellitus; erratic stomach emptying may result in poor glycemic control.. On the other hand, medications that mimic or enhance the function of the endogenous incretins retard gastric emptying to enhance glycemic control. In patients with obesity and type 2 diabetes, bariatric procedures alter food intake and weight; however, effects on glycemic control precede and are out of proportion with the degree of weight loss. The mechanisms responsible for the improved glycemic control after bariatric surgery are the subject of ongoing research, and include increased circulating incretins stimulated by the delivery of nutrients to the intestine, contributing to weight loss and independently to glycemic control. The stomach is not always a villain, but is an ally in patients with type 2 diabetes.

引用

页码：285 / 287

页数：3

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