Applications of carbon nanotubes-based biomaterials in biomedical nanotechnology

被引:123
作者
Polizu, Stefania [1 ]
Savadogo, Oumarou
Poulin, Philippe
Yahia, L'Hocine
机构
[1] Ecole Polytech, Montreal, PQ H3C 3A7, Canada
[2] Ctr Rech Paul Pascal, Bordeaux, France
关键词
carbon nanotubes; biomaterial; micro-devices; nanosensors; nanobiotechnology; biomedical; nanotechnology; nano-robots; biocompatibility; bioactivity;
D O I
10.1166/jnn.2006.197
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
One of the facets of nanotechnology applications is the immense opportunities they offer for new developments in medicine and health sciences. Carbon nanotubes (CNTs) have particularly attracted attention for designing new monitoring systems for environment and living cells as well as nanosensors. Carbon nanotubes-based biomaterials are also employed as support for active prosthesis or functional matrices in reparation of parts of the human body. These nanostructures are studied as molecular-level building blocks for the complex and miniaturized medical device, and substrate for stimulation of cellular growth. The CNTs are cylindrical shaped with caged molecules which can act as nanoscale containers for molecular species, well required for biomolecular recognition and drug delivery systems. Endowed with very large aspect ratios, an excellent electrical conductivity and inertness along with mechanical robustness, nanotubes found enormous applications in molecular electronics and bioelectronics. The ballistic electrical behaviour of SWNTs conjugated with functionalization promotes a large variety of biosensors for individual molecules. Actuative response of CNTs is considered very promising feature for nanodevices, micro-robots and artificial muscles. An description of CNTs based biomaterials is attempted in this review, in order to point out their enormous potential for biomedical nanotechnology and nanobiotechnology.
引用
收藏
页码:1883 / 1904
页数:22
相关论文
共 247 条
[1]   Carbon nanotubes: From macromolecules to nanotechnology [J].
Ajayan, PM ;
Charlier, JC ;
Rinzler, AG .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (25) :14199-14200
[2]   OPENING CARBON NANOTUBES WITH OXYGEN AND IMPLICATIONS FOR FILLING [J].
AJAYAN, PM ;
EBBESEN, TW ;
ICHIHASHI, T ;
IIJIMA, S ;
TANIGAKI, K ;
HIURA, H .
NATURE, 1993, 362 (6420) :522-525
[3]  
Ajayan PM, 2001, TOP APPL PHYS, V80, P391
[4]   Nanotubes from carbon [J].
Ajayan, PM .
CHEMICAL REVIEWS, 1999, 99 (07) :1787-1799
[5]   ELECTRONIC STATES OF CARBON NANOTUBES [J].
AJIKI, H ;
ANDO, T .
JOURNAL OF THE PHYSICAL SOCIETY OF JAPAN, 1993, 62 (04) :1255-1266
[6]  
[Anonymous], 1998, SCIENCE, V281, P941
[7]  
[Anonymous], 2002, EUROP CELLS MAT
[8]   Cell Culture on a Carbon Nanotube Scaffold [J].
Aoki, Naofurni ;
Yokoyama, Atsuro ;
Nodasaka, Yoshinobu ;
Akasaka, Tsukasa ;
Uo, Motohiro ;
Sato, Yoshinori ;
Tohji, Kazuyuki ;
Watari, Furnio .
JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2005, 1 (04) :402-405
[9]   Nanostressing and mechanochemistry [J].
Ausman, KD ;
Rohrs, HW ;
Yu, MF ;
Ruoff, RS .
NANOTECHNOLOGY, 1999, 10 (03) :258-262
[10]   Carbon nanotubes: nanomechanics, manipulation, and electronic devices [J].
Avouris, P ;
Hertel, T ;
Martel, R ;
Schmidt, T ;
Shea, HR ;
Walkup, RE .
APPLIED SURFACE SCIENCE, 1999, 141 (3-4) :201-209