PdII- and PtII-mediated polycyclization reactions of 1,5- and 1,6-dienes:: Evidence in support of carbocation intermediates

被引：59

作者：

Koh, JH ^{[1
]}

Gagné, MR ^{[1
]}

机构：

[1] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 26期

关键词：

carbocations; carbocycles; cyclization; palladium; platinum;

D O I：

10.1002/anie.200453913

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Pincer-ligated PdII and PtII dicationic complexes efficiently generate cations from 1,5- and 1,6-dienes. These transient cations can be selectively trapped with heteroatoms, alkenes, and through pinacol rearrangements. For example, trienyl-phenol 1 is converted into tetracyclic 2 in high yield and diastereomeric ratio (see scheme).

引用

页码：3459 / 3461

页数：3

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