Staphyloxanthin plays a role in the fitness of Staphylococcus aureus and its ability to cope with oxidative stress

被引：374

作者：

Clauditz, Alexandra ^{[1
]}

Resch, Alexandra ^{[1
]}

Wieland, Karsten-Peter ^{[1
]}

Peschel, Andreas ^{[1
]}

Goetz, Friedrich ^{[1
]}

机构：

[1] Univ Tubingen, D-72076 Tubingen, Germany

来源：

INFECTION AND IMMUNITY | 2006年 / 74卷 / 08期

关键词：

D O I：

10.1128/IAI.00204-06

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Staphyloxanthin is a membrane-bound carotenoid of Staphylococcus aureus. Here we studied the interaction of staphylloxanthin with reactive oxygen substances (ROS) and showed by comparative analysis of the wild type (WT) and an isogenic crtM mutant that the WT is more resistant to hydrogen peroxide, superoxide radical, hydroxyl radical, hypochloride, and neutrophil killing.

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收藏

页码：4950 / 4953

页数：4

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