Novel citric acid-based biodegradable elastomers for tissue engineering

被引:491
作者
Yang, J [1 ]
Webb, AR [1 ]
Ameer, GA [1 ]
机构
[1] Northwestern Univ, Dept Biomed Engn, Evanston, IL 60208 USA
基金
俄罗斯基础研究基金会;
关键词
D O I
10.1002/adma.200306264
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The synthesis and characterization of novel biodegradable elastomers, exemplified by poly(1,8-octanediol-co-citric acid), is reported. Biodegradation, mechanical, and biocompatibility data suggest very good potential for use as porous scaffolds in cardiovascular tissue engineering (see Figure). Material properties can be tailored by modulating the monomer ratio and post-polymerization conditions.
引用
收藏
页码:511 / +
页数:7
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