Combined directed ortho and remote metalation -: Cross-coupling strategies.: General method for benzo[a]carbazoles and the synthesis of an unnamed indolo[2,3-a]carbazole alkaloid

被引：83

作者：

Cai, XW ^{[1
]}

Snieckus, V ^{[1
]}

机构：

[1] Queens Univ, Dept Chem, Kingston, ON K7M 3N6, Canada

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 14期

关键词：

D O I：

10.1021/ol049780x

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient route to benzo[a]carbazoles via a metalation-cross-coupling sequence has been demonstrated (Scheme 2) and its application to the synthesis of the antitumor and antiviral alkaloid 6-cyano-5-methoxy-12-methylindolo[2,3-a]carbazole (5) has been achieved.

引用

页码：2293 / 2295

页数：3

共 16 条

[1]

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[2] Regiospecific synthesis of alkylphenanthrenes using a combined directed ortho and remote metalation -: Suzuki-Miyaura cross coupling strategy [J].